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MICROSATELLITE MARKERS FOR IDENTIFYING CANINE GENETIC DISEASES OR TRAITS

机译:鉴定犬类遗传疾病或性状的微卫星标记

摘要

Microsatellite markers are provided which are useful in identifying linked markers for canine genetic diseases and traits. The microsatellite markers are derived from regions of genomic DNA which contain a repeat motif, flanked by unique sequences. The number of units contained within the repeat motif is variable, such that various different alleles are present in any given population. The microsatellite markers and their progeny are especially useful in detecting genetic diseases not phenotypically visible and identifying carriers of recessive diseases, as illustrated in the figure. In a preferred embodiment, microsatellite markers are provided which may be used to detect the canine copper toxicosis gene.
机译:提供了微卫星标记,可用于识别犬遗传疾病和性状的连锁标记。微卫星标记来自基因组DNA区域,该区域包含一个重复的基序,两侧是独特的序列。重复基序中包含的单位数量是可变的,因此在任何给定的群体中都存在各种不同的等位基因。如图所示,微卫星标记及其后代在检测表型不可见的遗传疾病和鉴定隐性疾病的携带者方面特别有用。在一个优选的实施方案中,提供了可用于检测犬铜中毒基因的微卫星标记。

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