Macrophage inflammatory protein-3,-4 and-1 gamma (MACROPHAGE INFLAMMATORY PROTEINS-3,-4 AND-1 sg (g))

摘要

The present invention relates to human macrophage inflammatory protein-3, human macrophage inflammatory protein-4 and human macrophage inflammatory protein-_r, Polypeptides and DNA (RNA) encoding the polypeptides. The present invention also provides a method for producing said polypeptide by recombinant techniques and a method for producing an antibody against said polypeptide. The present invention also provides antagonists / inhibitors to said polypeptides that inhibit the action of said polypeptides. Another aspect of the invention provides a combination of a polypeptide of the invention and a suitable pharmaceutically acceptable carrier, which provides a therapeutically effective amount of the polypeptide for treatment of a variety of related diseases.