METHOD OF SYNTHESIS OF DERIVATIVES OF 2-CHLORO-NITROQUINOLINEAMINES, METHOD OF SYNTHESIS OF 2-CHLORO-3,4-DIAMINOQUINOLINES, METHOD OF SYNTHESIS OF DERIVATIVES OF 4-CHLORO-1H-IMIDAZO-4,5-C-QUINOLINES, METHOD OF SYNTHESIS OF DERIVATIVE OF 1H-IMIDAZO-4,5-C-QUINOLINES, 2-CHLORO-3-NITROAMINOQUINOLINE, 2-CHLORO-3,4-DIAMINOQUINOLINE

摘要

FIELD: organic chemistry. SUBSTANCE: products: derivatives of 4-chloro-1H-imidazo-[4,5-c] -quinolines, intermediate compounds for their synthesis. Reagent 1: 2,4-dichloro-3-nitroquinoline. Reagent 2: amine R-NH. Reaction conditions: organic solvent, base and synthesis of the corrersponding chloronitrodiaminoquinoline that is reduced to the corresponding chlorodiaminoquinoline and the latter interacts with trialkylfluoroether. EFFECT: improved method of synthesis. 6 cl