where: R1 means C1-6-alkoxy-, alkenyloxy-, alkynyloxy-, cycloalkyloxy-, aryloxy-, aralkyloxy-, hydroxyl, nitro-, cyano-, formyl, C1-6-acyl or C1-6-alkylcyano-group, or halogen atom; R2 means C1-6-alkyloxy-, alkenyloxy-, alkynyloxy-, cycloalkyloxy-, aryloxy-, aralkyloxy- or hydroxyl group; R1 and R2 together form alkylenedihydroxy-group, and R3 and R4 mean C1-6-alkyl group. Synthesized compounds show pharmacological activity. Invention relates to also pharmaceutical compositions containing compounds of the formula (I) and methods of preparing these pharmaceutical compositions. EFFECT: higher efficiency."/> METHOD OF SYNTHESIS OF BENZOPYRANE DERIVATIVES (VARIANTS), METHOD OF SYNTHESIS OF CHROMANONE DERIVATIVES (VARIANTS), DERIVATIVES OF BENZOPYRANE AND CHROMANONE, PHARMACEUTICAL COMPOSITION AND METHOD OF ITS PREPARING
首页> 外国专利> METHOD OF SYNTHESIS OF BENZOPYRANE DERIVATIVES (VARIANTS), METHOD OF SYNTHESIS OF CHROMANONE DERIVATIVES (VARIANTS), DERIVATIVES OF BENZOPYRANE AND CHROMANONE, PHARMACEUTICAL COMPOSITION AND METHOD OF ITS PREPARING

METHOD OF SYNTHESIS OF BENZOPYRANE DERIVATIVES (VARIANTS), METHOD OF SYNTHESIS OF CHROMANONE DERIVATIVES (VARIANTS), DERIVATIVES OF BENZOPYRANE AND CHROMANONE, PHARMACEUTICAL COMPOSITION AND METHOD OF ITS PREPARING

机译:苯并吡喃衍生物(变体)的合成方法,苯并吡喃酮和苯甲酮的衍生物,药物组合物及其制备方法

摘要

FIELD: organic chemistry. SUBSTANCE: product: benzopyrane derivatives of the formula (I) where: R1 means C1-6-alkoxy-, alkenyloxy-, alkynyloxy-, cycloalkyloxy-, aryloxy-, aralkyloxy-, hydroxyl, nitro-, cyano-, formyl, C1-6-acyl or C1-6-alkylcyano-group, or halogen atom; R2 means C1-6-alkyloxy-, alkenyloxy-, alkynyloxy-, cycloalkyloxy-, aryloxy-, aralkyloxy- or hydroxyl group; R1 and R2 together form alkylenedihydroxy-group, and R3 and R4 mean C1-6-alkyl group. Synthesized compounds show pharmacological activity. Invention relates to also pharmaceutical compositions containing compounds of the formula (I) and methods of preparing these pharmaceutical compositions. EFFECT: higher efficiency.
机译:领域:有机化学。物质:产品:式(I)的苯并吡喃衍生物其中:R 1 表示C 1-6 -烷氧基-,烯基氧基-,炔基氧基-,环烷氧基-,芳氧基-,芳烷氧基-,羟基,硝基-氰基,甲酰基,C 1 -6 -酰基或C 1-6 -烷基氰基或卤素原子; R 2 是指C 1-6 -烷氧基-,烯基氧基-,炔基氧基-,环烷氧基-,芳氧基-,芳烷氧基-或羟基; R 1 和R 2 一起形成亚烷基二羟基,R 3 和R 4 均表示C 1-6 -烷基。合成的化合物具有药理活性。本发明还涉及含有式(I)化合物的药物组合物和制备这些药物组合物的方法。效果:更高的效率。

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