METHOD OF PREPARING PIPERIDONE-4 (VARIANTS) DERIVATIVES AND LOWER ALKYL ESTER DERIVATIVES OF 3-(N-LOWER ALKYL-N- 3-2-CARBOLOWER ALKOXY LOWER ALKYL) (AMINO) 2,3-ENE ACIDS

摘要

FIELD: chemical industry. SUBSTANCE: present invention describes methods of preparing piperidone derivatives by reductive cyclization of compounds of formula (II) followed by cyclization and treatment in acid medium. Present invention also describes novel derivatives of 3- (N-lower alkyl-N-(3-(2-carbolower alkoxy lower alkyl) amino-2,3-unsaturated carboxylic acids of general formula II: wherein R1-R7 is each independently hydrogen, phenyl, lower alkoxy or lower alkyl optionally substituted by phenyl or lower alkoxy. EFFECT: more efficient preparation method. 4 cl, 2 tbl