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Enhancement of ribozyme catalytic activity by a neighboring facilitator oligonucleotide
Enhancement of ribozyme catalytic activity by a neighboring facilitator oligonucleotide
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机译:邻近的辅助寡核苷酸增强核酶的催化活性
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摘要
Methods are disclosed for increasing ribozyme catalytic activity without reducing specificity, which methods comprise contacting an RNA molecule with a ribozyme and a facilitator oligonucleotide. P PThe present invention further provides compositions comprising a ribozyme and an effective amount of a facilitator oligonucleotide.
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