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Chimeric immunocompromised mammal comprosing vascularized fetal organ tissue
Chimeric immunocompromised mammal comprosing vascularized fetal organ tissue
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机译:嵌合免疫受损的哺乳动物,侵害了血管化的胎儿器官组织
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摘要
Xenogeneic tissue is introduced into an immunocompromised host for interacting with agents and using such interaction for evaluating efficacy of drugs and vaccines, producing xenogeneic monoclonal antibodies, evaluating the effect of the various agents on specific tissues and the like. Particularly, drugs can be evaluated for their efficacy against a wide variety of pathogens which infect xenogeneic tissue, agents can be evaluated for their effect on the xenogeneic immune system and monoclonal antibodies to a predetermined epitope may be produced.
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