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Mac-1 I-domain protein useful in blocking neutrophil adhesion and migration
Mac-1 I-domain protein useful in blocking neutrophil adhesion and migration
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机译:Mac-1 I结构域蛋白可用于阻止中性粒细胞粘附和迁移
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摘要
An isolated and purified protein of the I-Domain from the human leukocyte beta 2-integrin Mac-1, expressed in recombinant Escherichia coli as a soluble fusion protein with glutathione S-transferase (GST). The protein, a functional derivative, fragment, analog or chemical derivative of such fragment is useful in the treatment of inflammation by interfering with the cell adhesion mechanism to block adhesion and migration of neutrophils.
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