The phthalide derivative and killer cell medicine null of the uterus cervix cancer cell which designates this as the

摘要

NEW MATERIAL:6-[2' E)-3',7'-Dimethyl-5'-oxo-2',6'-octadienyl]-7-hydroxy-5- methoxyphthalide expressed by the formula. USE:A cell-killing agent of cervical carcinoma cell. PREPARATION:A fruit body of Hericium erinaceum is subjected to extraction treatment with a homogeneous system consisting of water and an organic solvent (e.g. methanol or acetone) and the organic solvent is evaporated from the extracted liquid subjected to solid-liquid separation by filtration, etc., to afford a water phase. An organic solvent layer is collected by subjecting the water phase to liquid distribution treatment with a mixed system of water and organic solvent and the organic solvent is evaporated from the organic solvent layer to give the dried material. The dried material is subjected to chromatography fraction treatment and recrystallization treatment.