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Antifungal Compound of tetrahydrofuran, a Pharmaceutical composition containing them, their use to prepare an Antifungal medication deester amino acid and a Salt thereof

机译:四氢呋喃的抗真菌化合物,包含它们的药物组合物,其在制备抗真菌药物脱酯氨基酸及其盐中的用途

摘要

The Invention relates to a compound represented by the formula selected from the group consisting of (IA) or (IB), where X is selected regardless of the group formed by F and Cl, BR and CF3, is n or CH,R1 is an alkyl group (C3 to C8) cadenaramif ING or not branched substituted by one or two parts hidroxilasy its ester (e.g. Ester Polyether Ester, Heterocyclic,Amino Acid or its Ester phosphate ester) or its pharmaceutically acceptable Salt suitable for their composiciu00f3nfarmacu00e9utica trat ar and / or prevent fungal infections and the use of such compounds to prepareAntifungal medicines.
机译:本发明涉及由选自(IA)或(IB)的式表示的化合物,其中X与F和Cl,BR和CF 3形成的基团无关而选择为n或CH,R 1为-。烷基(C3至C8)萘甲酰胺ING或未被一或两部分羟乙基化的酯(例如酯聚醚酯,杂环,氨基酸或其酯磷酸酯)或其药学上可接受的盐,适用于其composici u00f3nfarmac u00e9utica治疗和/或预防真菌感染以及使用此类化合物制备抗真菌药物。

著录项

  • 公开/公告号AR003437A1

    专利类型

  • 公开/公告日1998-08-05

    原文格式PDF

  • 申请/专利权人 SCHERING CORPORATION;

    申请/专利号AR20100318996

  • 发明设计人

    申请日1996-06-18

  • 分类号C07D405/14;A61K31/41;

  • 国家 AR

  • 入库时间 2022-08-22 02:58:51

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