首页> 外国专利> Polynucleotide that encodes for an accessory Protein for Human interleukin-1 receptor Accessory Protein, such a Vector, a celulahuesped, an Antibody that binds to the Protein.A Pharmaceutical composition that comprises a method for preparing the

Polynucleotide that encodes for an accessory Protein for Human interleukin-1 receptor Accessory Protein, such a Vector, a celulahuesped, an Antibody that binds to the Protein.A Pharmaceutical composition that comprises a method for preparing the

机译:编码人白介素1受体辅助蛋白辅助蛋白的多核苷酸,例如载体,celulahuesped,与该蛋白结合的抗体。一种药物组合物,包括制备该蛋白的方法

摘要

The invention provides for the first time an auxiliary protein of human 1-1 receptor, which can be used to regulate 1-1 effect. The isolation of this protein inhibits the effect of IL-1 on cells. Therefore, one aspect of isolation is to provide this protein to treat the pathological antidote caused by excessive activity of IL-1 cells by increasing the additional protein of IL-1R human receptor (IL-1R). (ACP) is enough to inhibit the activation of IL-1 cells. This method can also be modified.Protein can be used to tracking agent for medicine products The invention also includes polynucleotide encoding the protein, a vector, a host cell, a molten protein containing the protein, an antibody specially related to the protein, and a pharmaceutical component containing the protein, 2. Protein inhibition procedures and the use of proteins as therapeutic substances for the treatment of inflammatory or immune responses and / or for the control and prevention of inflammatory or immune activity of mesothelioma-1,Other diseases and / or diseases.
机译:本发明首次提供了人1-1受体的辅助蛋白,其可用于调节1-1作用。该蛋白的分离抑制了IL-1对细胞的作用。因此,分离的一个方面是通过增加IL-1R人类受体(IL-1R)的另外的蛋白质来提供该蛋白质以治疗由IL-1细胞的过度活性引起的病理解毒剂。 (ACP)足以抑制IL-1细胞的激活。蛋白质也可用于追踪药物。本发明还包括编码该蛋白质的多核苷酸,载体,宿主细胞,含有该蛋白质的熔融蛋白质,与该蛋白质特别相关的抗体和2.蛋白质抑制程序,以及蛋白质作为治疗炎症或免疫反应和/或控制和预防间皮瘤-1,其他疾病和/或炎症或免疫活性的治疗物质的用途疾病。

著录项

  • 公开/公告号AR003919A1

    专利类型

  • 公开/公告日1998-09-30

    原文格式PDF

  • 申请/专利权人 F. HOFFMANN-LA ROCHE AG.;

    申请/专利号AR20100109596

  • 发明设计人

    申请日1996-01-19

  • 分类号C12N15/02;A61K38;A61K38/20;A61K39/395;A61P3/08;A61P11;A61P17;A61P29;A61P35/02;A61P37;C07K14/715;C07K16/24;C07K16/28;C12N5;C12N5/10;C12N15;C12N15/09;C12N15/12;C12N15/63;C12P21/08;C12R1/91;

  • 国家 AR

  • 入库时间 2022-08-22 02:58:47

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号