Human Antibody that binds to the Protein and Cell MN, vector comprising the polynucleotide encoding Said Antibody, Antibody Preparation method.Composition containing useful in the treatment of disorders involving the MN Protein.

摘要

Purified Human Antibody that binds to the Protein articuerpo MN. Nucleotide sequence encoding an Antibody Purified Human where the Antibody binds to the Protein MN.AN EXPRESSION vector comprising the polynucleotide above. A host Cell comprising the above-mentioned expression vector.Preparation method of a Human Antibody.That includes the steps of: Growing conditions in the host Cell which Express and purify the Antibody; Human Antibody obtained from the cultivation of the host Cell; useAn effective amount of a compound of Antibody of Human MN, in which the compound includes an Antibody of MN and a cytotoxic Agent,This can include ahgente cytotoxic cell death in these cells that express the MN for the treatment of the Human disorder in which the Protein is expressed in certain MNCells. Pharmaceutical composition comprising a Human Antibody that binds to the Protein MN and a vehicle acceptable for pharmaceutical use.