Xanthia compounds having terminally amino-terminated alkynol side chains

摘要

omega -Amino-hydroxyalkynyl substituted xanthine derivatives of formula (I) are new: R1 and/or R3 = group of formula (a) or (b); and when only one of R1 and R3 is group (a) or (b) the other is H or R8; R8 = 1-6C alkyl, 3-6C cycloalkyl or 4-8C cycloalkyl-alkyl; R2 = 1-5C alkyl, 3-6C cycloalkyl or 4-8C cycloalkyl-alkyl; R4 = H or 1-3C alkyl; R5-R7 = H, 1-6C alkyl, 3-6C cycloalkyl, 4-8C cycloalkyl-alkyl, Ar-1-2C alkyl or tri(1-4C alkyl)silyl; or NR5R6 = 4-7 membered saturated ring optionally substituted by 1-4 1-4C alkyl and/or containing O, S, SO, SO2 or NR13 in place of 1 CH2; R13 = H, 1-3C alkylcarbonyl or 1-4C alkyl; A = 1-6C alkylene; Z- = inorganic or organic acid anion.