USE OF 1,2-BRIDGED 1,4-DIHYDROPYRIDINES, 1,2-BRIDGED 1,4-DIHYDROPYRIDINES, PROCESS OF THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEREOF

摘要

The use of 1,2-alkylene-bridged 3,5-diacyl-1,4-dihydro-pyridine derivs. of formula (I) is claimed in the prepn. of selective potassium channel modulating medicaments for treating CNS disorders. The medicaments are also claimed. R1 = 6-10C aryl (opt. substd. by 1-5 of NO2, CN, halogen, CF3 and 1-6C alkylthio); R2, R3 = 1-8C alkyl, 1-8C alkoxy or phenyl; a = 1-3; R4 = Me; or R3 + R4 = (CH2)3 or CH2CMe2CH2.