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N-Substituted 4-Pyrimidinamines and Pyrimidine Diamines, Methods for their Preparation and Their Applications as a Doctor
N-Substituted 4-Pyrimidinamines and Pyrimidine Diamines, Methods for their Preparation and Their Applications as a Doctor
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机译:N-取代的4-嘧啶胺和嘧啶二胺,其制备方法及其在医生中的应用
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摘要
This invention relates to N-heteroaryl-4-pyrimidinamines of the formula CHEM where R1 is hydrogen, loweralkyl, aryl, or arylloweralkyl; R2 and R3 are independently hydrogen or loweralkyl, or R2 and R3 taken together are aryl; R4 and R5 are independently hydrogen or loweralkyl, or R4 and R5 taken together are aryl; X is hydrogen, halogen, cyano, nitro, amino, loweralkyl, loweralkoxy, trifluoromethyl or CHEM where Y is hydrogen, halogen or loweralkyl; m is an integer of 1 to 3; and the pharmaceutically acceptable acid addition salts thereof and where applicable the geometrical and optical isomers and racemic mixtures thereof. The compounds of this invention display utility as memory enhancing agents and as analgesic agents.
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