Montelukast or a pharmaceutically acceptable salt of montelukast, in particular the sodium salt of montelukast

摘要

Compounds having the formula I: CHEM are leukotriene antagonists and inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis, and allograft rejection.