(2R-CIS)-4-4-4-4-(5-(2,4-DIHALOPHENYL)-TETRAHYDRO-5-(1H-1,2,4-TR IAZOL-1-YLMETHYL)-TETRAHYDROFURAN-3-YLMETHOXYPHENYL2,4-DIHYDRO-2- ESTERS AND ETHERS OF MONO- OR DIHYDROXY-SUBSTITUTED (C4-C5) ALKYL-3H-1,2,4-TRIAZOL-3-ONE

摘要

A compound represented by formula (I), wherein X is independently both F or both Cl or one X is independently F and the other is independently Cl; R1 is a straight or branched chain (C4 to C5) alkyl group substituted by one or two amino acid ester grou ps convertible in vivo into a hydroxy group or a pharmaceutically acceptable salt thereof and pharmaceutical compositions thereof useful for treating and/or preventing fungal infections are disclosed.