probe catheter for the treatment of cancer of organs parenchimatosi with interstitial hyperthermia induced by radio frequency

• 1. 中空器官射频消融导管探头 [P] . 中国专利： CN110974411A . 2020-04-10
• 2. 一种射频消融导管以及包含该射频消融导管的治疗装置 [P] . 中国专利： CN205073019U . 2016-03-09
• 3. probe catheter for the treatment of cancer of organs parenchimatosi with interstitial hyperthermia induced by radio frequency [P] . IT1290866B1 . 1998-12-14

  机译： 探头导管治疗射频诱导的间质热器官实质癌

• 4. probe catheter for the treatment of cancer of organs parenchimatosi with interstitial hyperthermia induced by radio frequency [P] . ITMI962745D0 . 1996-12-24

  机译： 探头导管治疗射频诱导的间质热器官实质癌

• 5. improvements to a probe catheter for the treatment of tumorimediante interstitial hyperthermia induced by radio frequency. [P] . IT1309179B1 . 2002-01-16

  机译： 探针导管的改进，用于治疗射频诱发的肿瘤病灶间质热疗。

• 1. Si nanoparticles as sensitizers for radio frequency-induced cancer hyperthermia [C] . A. V. Kabashin, K. P. Tamarov, Yu.V. Ryabchikov, Synthesis and photonics of nanoscale materials XIII . 2016
• 2. Magnetic Resonance-guided High Intensity Focused Ultrasound (MRgHIFU) Induced Hyperthermia (HT) for Treatment of Cervical Cancer [D] . Zhu, Lifei. 2021
• 3. Radio frequency radiation-induced hyperthermia using Si nanoparticle-based sensitizers for mild cancer therapy [O] . Konstantin P. Tamarov, Liubov A. Osminkina, Sergey V. Zinovyev, -1
• 4. Radio frequency radiation-induced hyperthermia using Si nanoparticle-based sensitizers for mild cancer therapy [O] . Tamarov, Konstantin P., Osminkina, Liubov A., Zinovyev, Sergey V., 2014

• 1. Non-Thermal Radio Frequency Stimulation of Tubulin Polymerization in Vitro: A Potential Therapy for Cancer Treatment [J] . John T. Butters ,Xavier A. Figueroa ,Bennett Michael Butters . 生物物理学期刊（英文） . 2014,第4期
• 2. BACKGROUND： Vibrio vulnifi cus inside the body could activate the NF-!B signaling pathwayand initiate the inflammatory cascade. The lung is one of the earliest organs affected by sepsisassociated with acute lung injury. High mobility group protein B1 （HMGB1） is an important late-actingpro-infl ammatory cytokine involving in the pathophysiology of sepsis. It is also involved in the injuryprocess in the lung, liver and intestine. There has been no report on the involvement of HMGB1 inVibrio vulnifi cus sepsis-induced lung injury.METHODS： Sixty rats were randomly divided into a normal control group （group A, n=10） anda Vibrio vulnificus sepsis group （group B, n=50）. Sepsis was induced in the rats by subcutaneousinjection of Vibrio vulnificus （concentration 6×108 cfu/mL, volume 0.1 mL/100g）） into the left lowerlimbs. The rats in group B were sacrifi ced separately 1, 6, 12, 24, and 48 hours after the infection.Their lungs were stored as specimens, lung water content was measured, and lung pathology wasobserved under a light microscope. The expressions of the HMGB1 gene and protein in the lungswere detected by RT-PCR and Western blot. Data were analyzed with one-way analysis of variance（ANOVA） and the LSD method for pair-wise comparison between the two groups. P〈0.05 wasconsidered statistically signifi cant.RESULTS： Compared to group A （0.652±0.177）, HMGB1 mRNA expression in the lungs ofgroup B was signifi cantly higher at 0 hour （1.161±0.358, P=0.013）, 24 hours （1.679±0.235, P=0.000）,and 48 hours （1.258±0.274, P=0.004） （P〈0.05）, and peaked at 24 hours. Compared to group A（0.594±0.190）, HMGB1 protein expression at 6 hours （1.408±0.567, P=0.026） after infection wassignificantly increased （P〈0. 05）, and peaked at 24 hours （2.415±1.064, P=0.000） after infection.Compared to group A （0.699±0.054）, lung water content was significantly increased at 6 hours（0.759±0.030, P=0.001）,12 hours （0.767±0.023, P=0.000）, 24 hours （0.771±0.043, P=0.000） and 48hours （0.789±0.137, P=0.000） after infection （P〈0.05）. Compared to group A, pathological changesat 12 hours in group B indicate marked pulmonary vascular congestion, interstitial edema andinfl ammatory infi ltration. Alveolar cavity collapse and boundaries of the alveolar septum could not beclearly identifi ed.CONCLUSION： Vibrio vulnifi cus sepsis can lead to injury in rat lungs, and increased HMGB1expression in lung tissue may be one of the mechanisms for injury from Vibrio vulnifi cus sepsis. [J] . Qiao-meng Qiu ,Zhong-wang Li ,Lu-ming Tang . 世界急诊医学杂志(英文) . 2011,第4期
• 3. Radio Frequency Tank Circuit for Probing Planar Lipid Bilayers [J] . Abhishek Bhat ,Jonathan Rodriguez ,Hua Qin . 软纳米科学报（英文） . 2013,第4期
• 4. Diagnostics of Parameters by Optical Emission Spectroscopy and Langmuir Probe in Mixtures (SiH_4/C_2H_4/Ar) Radio-Frequency Discharge [J] . 吴静 ,张鹏云 ,孙继忠 . 等离子体科学与技术：英文版 . 2011,第5期
• 5. Treatment of Interstitial Peumopathy by Fei Tong Oral Liquid in the Malignant Tumor Patients after Radio-and/or Chemotherapy [J] . 陶凯 ,周晓园 ,毛树章 . 中医杂志：英文版 . 2003,第1期
• 6. 经肝动脉栓塞化疗序贯联合射频消融和细胞因子诱导的杀伤细胞治疗肝细胞癌的随机研究 [C] . 赵明 ,张亮 ,高飞 . 中国(第七届)肿瘤微创治疗学术大会 . 2011
• 7. 低氧诱导因子1α、上皮间质化相关蛋白及钙结合蛋白在乳腺非特殊型浸润性导管癌不同分子亚型中的表达及相关性研究 [A] . 袁媛 . 2016