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PEPTIDES, DERIVED FROM VIRUS-HIV-HELLEN-GLYCOPROTEINES, THE USE THEREOF FOR DETECTING INFECTION OF THESE VIRUSES AND FOR THE VACCINATION AGAINST AIDS
PEPTIDES, DERIVED FROM VIRUS-HIV-HELLEN-GLYCOPROTEINES, THE USE THEREOF FOR DETECTING INFECTION OF THESE VIRUSES AND FOR THE VACCINATION AGAINST AIDS
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机译:源自病毒-HIV-海伦-糖蛋白的肽,其用于检测这些病毒的感染和用于艾滋病毒疫苗接种的用途
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摘要
Peptides which issue from the glycoprotein envelope of the HIV virus and corresponding to one of the following formulae: X-Arg-Ile-Leu-Ala-Val-Glu-Arg-Tyr-Leu-Lys-Asp-Gln-Gln-Leu-Leu-Gly-Ile- Trp-Gly-Cys-Ser-Gly-Lys-Leu-Ile-Cys-Z (I X-Ala-Ile-Glu-Lys-Tyr-Leu-Gln-Asp-Gln-Ala-Arg-Leu-Asn-Ser-Trp-Gly-Cys- Ala-Phe-Arg-Gln-Val-Cys-Z (II in which X represents an NH2 group which is free or aminated by one or two alkyl groups comprising 1 to 5 carbon atoms, and Z represents either a free OH or alkoxy group, containing in the latter case an alkyl group comprising 1 to 5 carbon atoms, and in which at least one of the Cys residues is deleted, substituted or protected. Use in the detection of an infection due to HIV-1 and/or HIV-2 virus and in vaccination against AIDS.
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