首页> 外国专利> CRYSTALLINE FORMS OF ENDO-2,3-DIHYDRO-N- (8-METHYL-8-AZABICICLO (3.2.1) OCT-3-IL) -2-OXO-1H-BENZMIDAZOLE-1-CARBOXAMIDE AND HYDROCHLORIDE MONOHYDRATE ENDO-3-ETHYL-2,3-DIHYDRO-N- (8-METHYL-8-AZABICICLO (3.2.1) OCT-3-IL) -2-OXO-1H-BENCIMIDAZOL-1-CARBOXAMID HYDROCHLORIDE

CRYSTALLINE FORMS OF ENDO-2,3-DIHYDRO-N- (8-METHYL-8-AZABICICLO (3.2.1) OCT-3-IL) -2-OXO-1H-BENZMIDAZOLE-1-CARBOXAMIDE AND HYDROCHLORIDE MONOHYDRATE ENDO-3-ETHYL-2,3-DIHYDRO-N- (8-METHYL-8-AZABICICLO (3.2.1) OCT-3-IL) -2-OXO-1H-BENCIMIDAZOL-1-CARBOXAMID HYDROCHLORIDE

机译：ENDO-2,3-二氢-N-（8-甲基-8-偶氮二氯（3.2.1）OCT-3-IL）-2-OXO-1H-苯并咪唑-1-甲酰胺和氢氧一酸乙酯ENDO-3的晶体形式-乙基-2,3-二氢-N-（8-甲基-8-氮杂双（3.2.1）OCT-3-IL）-2-OXO-1H-苯甲咪唑-1-甲酰胺氢氯化物

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ENDO-2,3-DIHYDRO-N- (8-METHYL-8-AZABICICLO [3-2,1] OCT-3-IL) -2-OXO-1H-BENZIMIDAZOLA-1-CARBOXAMIDE PRESENTATION CRYSTALLINE HYDROCHLORIDE MONOHYDRATES AND OF ENDO-3-ETHYL-2,3-DIHYDRO-N- (8-METHYL-8-AZABICICLO [3.2.1] OCT-3-IL) 2-OXO1H-BENZIMIDAZOLA-1-CARBOXAMIDE OF THE FORMULA I (COMPOUND 2A: R = H) (COMPOUND 2B: R = C2H5), THE PROCESS FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM ARE ALSO PRESENTED.

机译：ENDO-2,3-二氢-N-（8-甲基-8-氮杂双[3-2,1] OCT-3-IL）-2-OXO-1H-苯并咪唑-1-碳酰胺呈递结晶的氢氯化氢一羟基合物和内酯式I的-3--3-乙基-2,3-二氢-N-（8-甲基-8-氮杂双[3.2.1] OCT-3-IL）2-OXO1H-苯并咪唑-1-甲酰胺（化合物2A：R ＝ H）（化合物2B：R ＝ C 2 H 5），还提出了含有它们的制备方法和药物组合物。

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公开/公告号ES2118846T3

专利类型
公开/公告日1998-10-01

原文格式PDF
申请/专利权人 BOEHRINGER INGELHEIM ITALIA S.P.A.;
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申请/专利号ES19930104564T
发明设计人 CEREDA ENZO;DUBINI ENRICA;EZHAYA ANTOINE;MAFFIONE GRAZIA;TURCONI MARCO;
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申请日1993-03-19
分类号C07D451/04;A61K31/46;
国家 ES
入库时间 2022-08-22 02:54:26

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