首页> 外国专利> CRYSTALLINE FORMS OF ENDO-2,3-DIHYDRO-N-(8-METHYL-8-AZABICYCLO (3.2.1)OCT-3-YL)-2-OXO-1H-BENZIMIDAZOLE-1-CARBOXAMIDE HYDROCHLORIDE MONOHYDRATE AND OF ENDO-3-ETHYL-2,3-DIHYDRO-N-(8-METHYL-8-AZABICYCLO (3.2.1)OCT-3-YL)-2-OXO-1H-BENZIMIDAZOLE-1-CARBOXAMIDE HYDROCHLORIDE MONOHYDRATE

CRYSTALLINE FORMS OF ENDO-2,3-DIHYDRO-N-(8-METHYL-8-AZABICYCLO (3.2.1)OCT-3-YL)-2-OXO-1H-BENZIMIDAZOLE-1-CARBOXAMIDE HYDROCHLORIDE MONOHYDRATE AND OF ENDO-3-ETHYL-2,3-DIHYDRO-N-(8-METHYL-8-AZABICYCLO (3.2.1)OCT-3-YL)-2-OXO-1H-BENZIMIDAZOLE-1-CARBOXAMIDE HYDROCHLORIDE MONOHYDRATE

机译：ENDO-2,3-二氢-N-（8-甲基-8-氮杂双环（3.2.1）OCT-3-YL）-2-OXO-1H-苯并咪唑-1-甲酰胺一氢氯化物的结晶形式3-ETHYL-2,3-DIHYDRO-N-（8-METHYL-8-AZABICYCLO（3.2.1）OCT-3-YL）-2-OXO-1H-BENZIMIDAZOLE-1-CARBOXAMIDE HOHDROHONONATERATE

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Crystalline monohydrates of endo-2,3-dihydro-N-(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)-2-oxo-1H-ben zimidazole-1-carboxamide hydrochloride and of endo-3-ethyl-2,3-dihydro-N-(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)-2-ox o-1H-benzimidazole-1-carboxamide hydrochloride of formula CHEM (Compound 2a: R = H (Compound 2b: R = C2H5 the processes for their preparation and pharmaceutical compositions containing them. IMAGE

机译：-2,3-二氢-N-（8-甲基-8-氮杂双环[3.2.1]辛-3-基）-2-氧代-1H-苯甲杂咪唑-1-羧酰胺盐酸盐的结晶一水合物和式的3-乙基-2,3-二氢-N-（8-甲基-8-氮杂双环[3.2.1]辛-3-基）-2-氧邻-1H-苯并咪唑-1-羧酰胺盐酸盐（化合物2a：R = H>（化合物2b：R = C2H5>制备方法和含有它们的药物组合物。<图像>

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公开/公告号HRP930479B1

专利类型
公开/公告日1999-10-31

原文格式PDF
申请/专利权人 MARCO TURCONI;
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申请/专利号HR1993P000479
发明设计人 MARCO TURCONI;
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申请日1993-03-23
分类号C07D451/04;A61K31/46;
国家 HR
入库时间 2022-08-22 02:27:26

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