Indexed library of recombinant congenic non-human animals

摘要

Libraries of genetically tagged recombinant congenic non-human animals are described that are useful for identifying the genetic basis of disease. The library shall preferably comprise, inter alia, recombinant congenic strains that have been verified as containing substantially discrete/contiguous regions of the donor parent genome in the context of at least one background genome. Additionally described are recombinant congenic non-human animals and strains, as well as methods for generating and detecting the same, that comprises genetically defined and contiguous regions of donor parent genome in the context of at least one background genome.