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RECOMBINANT ANTIBODIES FROM A PHAGE DISPLAY LIBRARY, DIRECTED AGAINST A PEPTIDE-MHC COMPLEX

机译:噬菌体展示文库针对肽-MHC复合物的重组抗体

摘要

The invention relates to a method of producing an antibody or an antibody fragment specifically recognizing a peptide-MHC complex. It also relates to antibodies and antibody fragments according to the invention which are conjugated to a pharmaceutical or to a superantigen. Furthermore, the invention relates to a pharmaceutical composition comprising antibodies or antibody fragments according to the invention for the prevention or treatment of infectious and autoimmune diseases, and cancer, and to compositions for the diagnosis of said diseases.
机译:本发明涉及产生特异性识别肽-MHC复合物的抗体或抗体片段的方法。它还涉及与药物或超抗原缀合的根据本发明的抗体和抗体片段。此外,本发明涉及用于预防或治疗传染性和自身免疫性疾病以及癌症的包含根据本发明的抗体或抗体片段的药物组合物,并且涉及用于诊断所述疾病的组合物。

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