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Recombinant antibodies from a phage display library, directed against a peptide-MHC complex

机译:来自噬菌体展示文库的针对肽-MHC复合物的重组抗体

摘要

The invention relates to a method of producing an antibody or an antibody fragment specifically recognizing a peptide-MHC complex. It also relates to antibodies and antibody fragments according to the invention that are conjugated to a pharmaceutical or to a superantigen. The invention relates to a pharmaceutical composition comprising antibodies or antibody fragments a according to the invention for the prevention or treatment of infectious and autoimmune diseases, cancer and to compositions for the diagnosis of said diseases.
机译:本发明涉及产生特异性识别肽-MHC复合物的抗体或抗体片段的方法。它还涉及与药物或超抗原偶联的根据本发明的抗体和抗体片段。本发明涉及用于预防或治疗感染性和自身免疫性疾病,癌症的包含根据本发明的抗体或抗体片段a的药物组合物,以及用于诊断所述疾病的组合物。

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