Transdermal administration of isobaroid dinitrate, a treatment for angina pectoris

摘要

The present invention relates to an apparatus for transdermal administration of isobarbide dinrate, which is a therapeutic agent for angina pectoris, and a method for preparing the same, which comprises forming a polymer matrix layer of a drug-solubilizing agent, a polymer matrix and a promoter for effective penetration of drugs on a laminate layer, And a peeling layer is formed thereon. The thus prepared percutaneous administration device has not only a large diffusion rate of drug but also little erythema and edema due to skin irritation.