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Method of ameliorating or preventing septic shock using a monoclonal antibody specific to cachectin/tumor necrosis factor
Method of ameliorating or preventing septic shock using a monoclonal antibody specific to cachectin/tumor necrosis factor
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机译:使用针对恶病质素/肿瘤坏死因子的单克隆抗体改善或预防败血性休克的方法
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摘要
The present invention pertains to the novel hybridoma SDW18.1. 1, hybridomas obtained from SDW18.1.1, monoclonal antibodies obtained from such hybridomas and derivatives of such monoclonal antibodies. The novel hybridomas are formed by fusion of cells from a mouse myeloma line and spleen cells from a mouse previously immunized with cachectin/TNF. Diagnostic and therapeutic utilities for the monoclonal antibodies and their derivatives are proposed, and testing procedures, materials in kit form and pharmaceutical compositions are likewise set forth.
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