Compound, processes for preparing a compound, treating neurogenic inflammation and rheumatoid arthritis, pharmaceutical composition, pharmaceutical compositions suitable for treating neurogenic inflammation, for treating neuropathy, for treating rheumatoid arthritis, for reducing blood glucose, for inhibiting cgrp activity, for treating migraine, to treat itching, and use of a compound

摘要

"COMPOUND, PROCESSES TO PREPARE A COMPOUND, TREAT NEUROGENIC INFLAMMATION AND RHEUMATOID ARTHRITIS, PHARMACEUTICAL COMPOSITION, PHARMACEUTICAL COMPOSITIONS SUITABLE TO TREAT NEUROGENIC INFLAMMATION, TO TREAT NEUROPATHIC TREATMENT, TO TREAT NEUROPATHY, TO TREAT IT TREAT MIGRAINE, TO TREAT ITCH, AND USE OF A COMPOUND ". The present invention relates to new N-substituted azaeterocyclic azaeterocyclic carboxylic acids of general formula (I): where X, Y, Z, R ^ 1 ^, R ^ 2 ^ er are as defined in the detailed part of the description, or their salts, processes for their preparation, compositions containing them and their use for the clinical treatment of painful, hyperalgesic and / or inflammatory conditions, in which C-fibers play a pathophysiological role, by eliciting pain or neurogenic inflammation , as well as its use to treat indications caused by or related to insulin secretion and circulation by antagonizing peptides.