FORMULATIONS CONTAINING MELATONIN TO BE TOPICALLY APPLIED FOR THE PURPOSE OF PROTECTING THE SKIN FROM OXIDATIVE DAMAGE

摘要

A method is disclosed for the utilization of topically applied melatonin forthe prevention ofoxidative damage in human skin induced by sunlight; i.e., a method forpreparing formulationscontaining melatonin for use as moisturizers, sunblocks, and sunscreens. Inaddition theformulations will contain one or more proteins that will preserve themelatonin from degradationwhile in storage, but will allow its controlled release for penetration intocells of the skin whentopically applied to the skin, in such a manner that serum melatoninconcentration is not raisedto supra-physiological levels that may induce adverse effects. In addition theformulation mayoptionally contain other antioxidants and cosmetic agents.