PROGESTIN THERAPY FOR CAUSING ENDOMETRIAL ATROPHY WHILE MAINTAINING AMENORRHEA

摘要

Disclosed is a progestin therapy to causeendometrial atrophy while maintaining amenorrhea in a woman,by constant vaginal administration of progestin twice perweek via a drug delivery system (or a pharmaceuticalcomposition) comprising a water-insoluble water-swellablecross-linked polycarboxylic acid polymer and 4% by weight ofprogestin.