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DETECTION AND INVESTIGATION OF BIOLOGICAL MOLECULES BY FOURIER TRANSFORM INFRA-RED SPECTROSCOPY
DETECTION AND INVESTIGATION OF BIOLOGICAL MOLECULES BY FOURIER TRANSFORM INFRA-RED SPECTROSCOPY
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机译:傅里叶变换红外光谱法检测和研究生物分子
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摘要
Method and apparatus to study biological molecules or biological components at or in self-assembled monolayers (SAMs) on metal surfaces (2) such as gold in aqueous environments (6) using attenuated total internal reflection Fourier transform infra-red (ATR-FTIR) spectroscopy are described. Said method may be used for e.g. the screening for effective substances suitable as agonists or antagonists or - if performed time resolved - for studying kinetics of interactions of e.g. biological molecules adsorption and desorption processes or for the development of materials and surfaces for biological or medical applications.
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