PEPTIDE DERIVED FROM AN ANTIGEN RECOGNIZED BY AUTOANTIBODIES FROM PATIENTS WITH RHEUMATOID ARTHRITIS, ANTIBODY DIRECTED AGAINST SAID PEPTIDE, A COMBINATORIAL ANTIGEN, AND A METHOD OF DETECTING AUTO-IMMUNE ANTIBODIES

摘要

The present invention relates to a kind of peptides, and from the antigen autoantibody identified, there is these peptides reactive autoimmune antibody to suffer from rheumatoid arthritis certainly. Peptide according to the present invention has the arginine residues of modification. The present invention also relates to the peptides of antibody and method to detect autoimmune antibody.