PEPTIDE DERIVED FROM AN ANTIGEN RECOGNIZED BY AUTOANTIBODIES FROM PATIENTS WITH RHEUMATOID ARTHRITIS, ANTIBODY DIRECTED AGAINST SAID PEPTIDE, A COMBINATORIAL ANTIGEN, AND A METHODOF DETECTING AUTO-IMMUNE ANTIBODIES

摘要

The invention relates to a peptide derived from an antigen recognized byautoantibodies, which peptide is reactive with autoimmuneantibodies from a patient suffering from rheumatoid arthritis. The peptideaccording to the invention possesses a modified arginine residue.The invention also relates to antibodies against the peptide and a method ofdetecting autoimmune antibodies.