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Novel fused pyrrole carboxamides; New species of gamma-aminobutyric acid brain receptor ligands
Novel fused pyrrole carboxamides; New species of gamma-aminobutyric acid brain receptor ligands
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机译:新型稠合吡咯羧酰胺;新型γ-氨基丁酸脑受体配体
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摘要
The present invention relates to a compound of the formula (I) or a pharmaceutically acceptable non-toxic salt thereof:;(I);In this formula,;G /RTI ;Q is an aryl substituent optionally mono-or disubstituted by hydroxy or halogen;;T is halogen, hydrogen, hydroxyl, amino, or alkoxy having 1 to 6 carbon atoms;;W is oxygen, nitrogen, sulfur or optionally substituted methylene;;X is hydrogen, hydroxyl or alkyl;;Z is an organic or inorganic substituent that optionally forms a ring with the substituent at the position of Q;;Independently represent an optionally substituted carbon chain;;k, m and n are independently 0 or an integer of 1 to 3;;R3, R4, R5And R6Are the same or different and represent organic or inorganic substituents.
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机译:本发明涉及式(I)的化合物或其药学上可接受的无毒盐:;(I);在该式中,G; Q是任选地被-或-被-取代的芳基取代基羟基;或卤素;; T为具有1-6个碳原子的卤素,氢,羟基,氨基或烷氧基;; W为氧,氮,硫或任选取代的亚甲基;; X为氢,羟基或烷基;; Z为氢有机或无机取代基,其任选地与取代基在Q的位置形成环;;独立地表示任选取代的碳链;; k,m和n独立地为0或1至3的整数;; R Sub 3 Sub>,R 4 Sub>,R 5 Sub>和R 6 Sub>相同或不同,表示有机或无机取代基。
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