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RECOMBINANT VARICELLA-ZOSTER VIRUS AND PROCESS FOR CONSTRUCTING SAME

机译:重组水痘-带状疱疹病毒及其构建方法

摘要

The present invention provides a live vaccine containing a controlled varicella zoster virus produced by inserting one or more genes selected from the gene group of the hepatitis B virus genome, the genomic DNA of the described virus, and the controlled virus described as an active ingredient. A diagnostic agent containing an antigen derived from a prophylactic virus and an antigen described is provided.;The chickenpox shingles virus of the present invention can be used as a multivalent vaccine having the same excellent immunity against chicken pox and hepatitis B, and its expression product and genomic DNA can be used as a multivalent diagnostic agent.
机译:本发明提供了一种活疫苗,其包含通过插入选自乙型肝炎病毒基因组的基因组的一种或多种基因,所述病毒的基因组DNA和被描述为活性成分的受控病毒而产生的受控水痘带状疱疹病毒。本发明的水痘带状疱疹病毒可以用作对水痘和乙型肝炎具有相同的优异免疫力的多价疫苗,并且可以使用含有上述预防性病毒和抗原的抗原的诊断剂。基因组DNA可以用作多价诊断剂。

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