RECOMBINANT VARICELLA-ZOSTER VIRUS AND PROCESS FOR CONSTRUCTING SAME

摘要

The present invention provides a recombinantvaricella-zoster virus prepared by inserting at least one kind of geneselected from a gene group of hepatitis B virus genome, agenomic DNA of said recombinant virus, a live vaccine containingsaid recombinant virus as an effective ingredient, an antigenderived from said recombinant virus, and diagnostic agentcontaining said antigen.The recombinant varicella-zoster virus of the presentinvention can be utilized as a multivalent vaccine Having anexcellent immunity effect both on chickenpox and hepatitis H,and the expression products and genomic DNA thereof may be usedas a multivalent diagnostic agent.