Method for controlling body fat and/or body weight in animals and pharmaceutical compositions for use therein comprising 20-carbon conjugated unsaturated fatty acids

摘要

Methods of inhibiting lipoprotein lipase and controlling the body fat and the body weight of an animal employ an effective amount of at least one 20 carbon, conjugated, unsaturated, fatty acid. Pharmaceutical compositions for use in the method are also disclosed. The 20-carbon conjugated fatty acids are selected from an eicosadienoic acid, an eicosatrienoic acid, and an eicosatetraenoic acid. Preferably, the fatty acids are 11,13-eicosadienoic acid; 12,14-eicosadienoic acid; 8,11, 13- eicosatrienoic acid; 5,8,11,13-eicosatetraenoic acid; 5,8,12,14- eicosatetraenoic acid, or an ester, salt, or mixture thereof.