5--Caboxamido or 5--fluoro--2', 3'--unsaturated or 3'-- modified-- pyrimidine nucleosides

摘要

A method and composition for the treatment of HIV and HBV infections in humans and other host animals is disclosed that includes the administration of an effective amount of a [5-carboxamido or 5- fluoro]- 2',3'-dideoxy-2',3'-didehydro-pyrimidine nucleoside or a [5- carboxamido or 5-fluoro]-3'-modified-pyrimidine nucleoside, or a mixture or a pharmaceutically acceptable derivative thereof, including a 5' or N. sup. 4 alkylated or acylated derivative, or a pharmaceutically acceptable salt thereof, in a pharmaceutically acceptable carrier.