Desmin enhancer sequences, vectors comprising these sequences and their uses in compositions for the expression of nucleotide sequences in transfected cells

摘要

The invention teaches modified desmin enhancer sequences which yield high level expression of operably linked DNA sequences. The claimed modified desmin enhancer sequences may be operably linked to genes encoding a protein. Further these modified desmin enhancer sequences may be placed into vectors including plasmids and transformed into cells including bacteria or myoblasts. Finally, these modified desmin enhancers may be used in methods of expression of proteins in the transformed bacteria or myoblasts.