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Identification of DNA-damaging substances by means of cell lines capable of overexpressing poly (ADP-ribose)--polymerase

机译:通过能够过度表达聚(ADP-核糖)-聚合酶的细胞系鉴定DNA损伤物质

摘要

The present invention relates to a DNA construct containing a cDNA sequence for human poly(ADP-ribose)-polymerase, cell lines containing the DNA construct, and a process for identifying DNA-damaging substances by means of these cell lines which overexpress poly(ADP-ribose) - polymerase.
机译:本发明涉及一种含有人聚(ADP-核糖)-聚合酶cDNA序列的DNA构建体,含有该DNA构建体的细胞系,以及利用这些过表达poly(ADP)的细胞系鉴定DNA损伤物质的方法。 -核糖)-聚合酶。

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