CARRIER FOR CULTURING T LYMPHOCYTE, PRODUCTION OF ACTIVATED T LYMPHOCYTE, KIT FOR PRODUCTION OF ACTIVATED T LYMPHOCYTE AND IMMUNE THERAPEUTIC AGENT

摘要

PROBLEM TO BE SOLVED: To obtain a carrier for culturing T lymphocyte, capable of providing an activated T lymphocyte hardly having risk due to contamination, etc., of various germs, etc., and excellent in storage stability to long-term storage and reliability of quality and performance, provide a method for producing activated T lymphocyte hardly having scattering of culturing efficiency of T lymphocyte and activation efficiency of culturing lymphocyte, etc., using the same carrier and obtain a kit for producing the activated T lymphocyte and an immune therapeutic agent suitable for adoptive immunotherapy of cancer, infectious disease, etc. SOLUTION: This carrier for culturing T lymphocyte comprises an insoluble carrier in which anti-CD3 antibody is fixed, whose surface is dried. This method for producing an activated T lymphocyte comprises culturing T lymphocyte by using the carrier for culturing T lymphocyte and liquid culture medium for culture. This kit for producing activated T lymphocyte comprises the carrier for culturing T lymphocyte and a culture medium for culture. This immune therapeutic agent comprises an activated T lymphocyte obtained by a method for producing the activated T lymphocyte.