Recombinant human interleukin 4 muteinas antagonists with high Affinity, Pharmaceutical composition, polinucleotida sequence, a host Cell unable to become a complete organism,AN EXPRESSION Vector and a method of implementation of the muteina antagonist expression vector to express Recombinant human il-4.

摘要

A very similar I-4 type mutual aid numbered according to wild I-4, wherein the mutual aid includes at least one ammonium substitute in the wild I-4 alpha or C-type propeller complex, and the mutual aid is combined with the I-4 ralfa receiver through latex, at least similar to the native spiral receiver of I-4 type. It is better to choose a replacement from a group of positions 13 and 16 of A-type propeller and positions 81 and 89 of C-type propeller. The most popular implementation is the re pairing of IL-4 human interactions, in which case the positional alternative is thr-asp. It also describes the composition of the drugUsing synthetic compounds, fungicidal sequences, and polynucleotides to code their interactions, transformed host cells, meteor antibodies, tests to determine the ability to interact, and a high affinity IL-4 symbiont, including its components.