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Injectable Veterinary Composition of Ivermectin Programmable release
Injectable Veterinary Composition of Ivermectin Programmable release
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机译:伊维菌素注射剂的兽医用成分
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摘要
A composition for injection of Ivermectin Release provides a PROGRAMMABLE PULSE sequence of release of Ivermectin, The Blood of the treated animals.The composition comprises a solution of 0.2% to 10% w / W of Ivermectin in a Solvent selected from among a mixture of Aluminium and caproic acid Glycerides,CAPRYLIC and capric in Equal Parts.The solution is used as a vehicle to suspend microspheres micronesa 100 200 Micron diameter of a biodegradable Polymer containing between 0.5 and 50% ivermectinThe microspheres can be formed by u00e1cidopolilu00e1ctico, poliglucolico acid or polylactic acid Copolymer - polilglucolico.The system multiliberador Programmable obtenidotambiu00e9n Matrix can be chosen with a biodegradable natural Polymers such as hardened Gelatin or albumen.In addition to the yglicolico lactic acid copolymers.The Natural Polymers may have been subjected to a hardening process to increase resistance to biological agents, for example,To treat with a solution of GLUTARALDEHYDE or heated until its temperature of coagulation Proteins.In One embodiment, are degelatinacargadas Ivermectin microspheres in an aqueous solution of 25% GLUTARALDEHYDE for 24 hours and were then Suspended in the solvent.Another realizacionincluye a suspension of a Copolymer of DL polylactic polyglycolic - 1: 1 with cargadasde Ivermectin microspheres.This relationship can servariada monomers to produce pulses of Ivermectin At intervals of length Programmable.
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