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Atropoisomeros 2 - (aryl or heteroaryl) - 3 - aryl 4 (3H) - quinazolinonas and Pharmaceutical compositions containing them

机译:Atropoisomeros 2-(芳基或杂芳基)-3-芳基4(3H)-喹唑啉酮和包含它们的药物组合物

摘要

2 - (aril or heterosexual) - 3-aril-4 (3H) - quinazolinonas de design (I) in which R2 is a phenyl group of pH2 formula, or a decadal or six member heterocyclic isomer; selected from design group (II),(III) o (IV)R3 is hydrogen, halogen-cn, NO2, CF3, tar (C1-C6) or Alcoy (C1-C6);R5 is hydrogen, hydrocarbon (C1-C6),a. Halogen, CF3, alcoxi (C1-C6) or asphalt (C1-C6);R6 is hydrogen or halogen; R7 is hydrogen or halogen; R8 is hydrogen halogen. It refers to 3-aril-4 (3H) - quinazine (I),Please indicate the salts and pharmaceutical formulations for which their drugs are acceptable, and the procedures for the treatment of neurodegenerative and trauma related diseases of the national health system.
机译:2-(芳基或异性)-3-芳基-4(3H)-设计(I)的喹唑啉酮,其中R 2为pH2式的苯基,或十年或六元杂环异构体;选自设计组(II),(III)o(IV)R3是氢,卤素-cn,NO2,CF3,焦油(C1-C6)或醇(C1-C6); R5是氢,烃(C1-C6 ),一种。卤素,CF3,酒精(C1-C6)或沥青(C1-C6); R6是氢或卤素; R7是氢或卤素; R 8为氢卤素。它是指3-aril-4(3H)-quinazine(I),请指出其药物可接受的盐和药物制剂,以及国家卫生系统与神经退行性疾病和创伤相关疾病的治疗程序。

著录项

  • 公开/公告号AR011170A1

    专利类型

  • 公开/公告日2000-08-02

    原文格式PDF

  • 申请/专利权人 PFIZER PRODUCTS INC.;

    申请/专利号AR1998P100871

  • 发明设计人

    申请日1998-02-26

  • 分类号C07D401/06;C07D403/06;C07D417/06;C07D401/14;C07D405/06;C07D239/91;A61K31/505;C07M7/00;

  • 国家 AR

  • 入库时间 2022-08-22 01:57:29

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