Zinc-free insulin crystals, therapeutic powder formulation, process for preparing zinc-free insulin crystals, use of zinc-free crystals, and process for the treatment of diabetes mellitus

摘要

"ZINC-FREE INSULIN CRYSTALS, THERAPEUTIC FORMULATION IN POWDER, PROCESS FOR THE PREPARATION OF ZINC-FREE INSULIN CRYSTALS, USE OF ZINC-FREE CRYSTALS, AND, PROCESS FOR THE TREATMENT OF MELLITUS DIABETES" Zinc-free insulin crystals a diameter below 10 µm suitable for pulmonary administration are described. Those described have a reduced tendency to associate in dry powder aggregates.