Improvement of the half life of movement of proteìnas fusion based on antibody.

摘要

"The improvement of the half life of movement of proteu00ecnas fusion based on antibody" are revealed processes to genetic construct and expression of fusion proteins on the basis of antibody with half VVisits of movement improved.The fusion protein of the present invention do not have the capacity to bind to Fc receptors for immunoglobulin.In both consequ00b3u00eancia of antibody isotype used for construction of the construction of protein and through mutagenese isotypes of antibody directed to that normally bind Fc receptors.The fusion proteins of the present invention may also contain a functional area capable of calling a receiver, of the protection of immunoglobulin.