首页> 外国专利> Compounds, pharmaceutical compositions, methods for inhibiting cell death in a cell or tissue, methods of treating or REDUCE cell death, treatment or prophylaxis of polycystic kidney or anemia / erythropoiesis in an animal way to protect an organ or tissue of mammals from extinction CELLS, METHOD FOR REDUCTION OR PREVENTION CELL DEFENSE IN ORGAN OR TREATMENT OF DONOR AFTER THEIR TRANSPLANTATION, THE WAY TO REDUCE OR PREVENT THE DESTRUCTION OF SPERM OR EGGS

Compounds, pharmaceutical compositions, methods for inhibiting cell death in a cell or tissue, methods of treating or REDUCE cell death, treatment or prophylaxis of polycystic kidney or anemia / erythropoiesis in an animal way to protect an organ or tissue of mammals from extinction CELLS, METHOD FOR REDUCTION OR PREVENTION CELL DEFENSE IN ORGAN OR TREATMENT OF DONOR AFTER THEIR TRANSPLANTATION, THE WAY TO REDUCE OR PREVENT THE DESTRUCTION OF SPERM OR EGGS

机译:化合物,药物组合物,抑制细胞或组织中细胞死亡的方法,治疗或减少细胞死亡的方法,以动物的方式治疗或预防多囊肾或贫血/红细胞生成,以保护哺乳动物的器官或组织免于灭绝的细胞,移植后减少或预防组织中细胞防御或治疗供体的方法,减少或预防精子或卵子破坏的方法

摘要

The present invention relates to new dipeptides represented by the general formula (I), where R-R and AA are defined in the specification. The present invention relates to the discovery of compounds having the formula (I), which are strong inhibitors of apoptotic cell death. Therefore, the inhibitors of the present invention can slow down or block cell death, which is observed in a number of clinical conditions involving loss of cells, tissues, or entire organs. The international application was published along with an international search report.
机译:本发明涉及由通式(I)表示的新的二肽,其中R-R和AA在说明书中定义。本发明涉及具有式(I)的化合物的发现,所述式(I)的化合物是凋亡细胞死亡的强抑制剂。因此,本发明的抑制剂可以减慢或阻断细胞死亡,这在许多涉及细胞,组织或整个器官丧失的临床状况中观察到。国际申请与国际检索报告一同发布。

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