Method for Identifying and Using Biosynthetic or Regulatory Genes to Improve Secondary Metabolite Production

摘要

Novel methods and compositions are provided for the enhanced production of secondary metabolites. Methods are provided for identifying sequences which when transformed into secondary metabolite producing hosts, enhance the production of secondary metabolite. The process is exemplified for penicillin. In addition, the P. chrysogenum acyltransferase gene has been isolated and sequenced.