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Pharmaceutical preparation controlled to release medicinal active ingredient at targeted site in intestinal tract.

机译:控制药物制剂以在肠道的目标部位释放药物活性成分。

摘要

A pharmaceutical preparation for oral administration which is controlled to release a medicinal active ingredient at a targeted site in the intestinal tract comprising (a) a core containing a medicinal active ingredient and (b) a press-coated layer comprising an enteric polymer, said layer being provided around the core. In the pharmaceutical preparation of the present invention, the medicinal active ingredient is not released during residence in the stomach and, after discharged from the stomach, until reaching a targeted site in the intestine, and thereafter is quickly released, so that the medicinal active ingredient is efficiently delivered to the targeted site in the intestinal tract.
机译:用于口服的药物制剂,其被控制以在肠道的目标部位释放药物活性成分,该药物制剂包括(a)包含药物活性成分的芯和(b)包含肠溶聚合物的压制包衣层,所述层围绕核心提供。在本发明的药物制剂中,药物活性成分在留在胃中的过程中不释放,并且在从胃排出后直至到达肠中的目标部位,然后迅速释放,从而使药物活性成分释放。被有效地递送到肠道的目标部位。

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