PHARMACEUTICAL PREPARATION CONTROLLED TO RELEASE MEDICINAL ACTIVE INGREDIENT AT TARGETED SITE IN INTESTINAL TRACT

摘要

A pharmaceutical preparation for oraladministration which is controlled to release a medicinalactive ingredient at a targeted site in the intestinaltract comprising(a) a core containing a medicinal active ingredient and(b) a press-coated layer comprising an enteric polymer,said layer being provided around the core. In thepharmaceutical preparation of the present invention, themedicinal active ingredient is not released from duringresidence in the stomach and, after discharged from thestomach, until reaching a targeted site in the intestine,and thereafter is quickly released, so that the medicinalactive ingredient is efficiently delivered to the targetedsite in the intestinal tract.