Farnesyl Transferase inhibitors combined with HMG CoA reductase Inhibitors for Cancer Therapy.

摘要

This Invention relates to the use of an inhibitor of farnesyltransferase (ftase) combined with statins inhibitor coenzyme A (HMG CoA reductase) to treat cancer in a mamifeRo. These chemical compounds have the structure (i), wherein R1, R2, R3 and R4 are functional groups described in the file.